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About Lyprinolâ
WHY IT WORKS
 The
process of inflammation
is highly complex and is
defined as the body's
reaction to physical,
chemical or biological
injury which, in a
normal healthy
individual, results in
the localization of the
problem and regeneration
or repair of the damaged
tissue. Unfortunately,
inflammatory response is
not always beneficial to
the individual.
 A
prime example is that of
osteoarthritis, an
inflammatory disease
which can effect all the
bone joints of the human
body but primarily
affects the "wear and
tear" joints of the
feet, knees, hands,
hips, shoulders, elbows
and back which have
usually had the effects
of many years of work
and sometimes injury.
In certain
circumstances, the
process itself can cause
damage and injury. The
auto-immune disease,
rheumatoid arthritis,
where the body attacks
itself, and the
hypersensitive states
leading to asthma and
anaphylactic shock, are
examples of uncontrolled
inflammatory responses.
Initiation and control
of the inflammatory
process is complex and
governed by an array of
biomolecular mechanisms.
One important
pro-inflammatory
mechanism is closely
associated with
cell-membrane bound
arachidonic acid, which
becomes converted into
other compounds in the
body which are potent
inflammation-supporting
substances.
 This
occurs by two major
pathways in our
metabolism:
The 5-lipoxygenase
pathway leading to the
formation of
leukotrienes, and
The cyclo-oxygenase
pathway which leads to
the formation of
prostaglandins and
thromboxanes.
Click to enlarge
Many of the products of
these pathways have
potent
inflammation-supporting
properties. For
instance, LTB 4 is a
potent chemotactic agent
capable of attracting
large numbers of
leucocytes (white blood
cells), to the site of
the injury. LTC 4, LTD
4, and LTE 4, which are
metabolites of LTB 4,
are potent
bronchoconstricting
agents and were formerly
identified as SRS-A's
(slow reacting substance
of anaphylaxis), a key
factor in anaphylactic
shock.
Currently used
anti-inflammatory drugs
function mainly by
inhibiting the
cyclo-oxygenase pathway.
In view of the important
functions of the
inflammatory process
ascribed to the
lipoxygenase pathway,
there has been
considerable scientific
effort to develop a
5-lipoxygenase pathway
inhibitor over the past
decade. Lyprinolâ is a
5-lipoxygenase pathway
inhibitor which is both
effective and safe.
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